Drug Sensitivity Test of M, leprae using Liquid Media
نویسندگان
چکیده
منابع مشابه
Viability and drug sensitivity of M. leprae isolated from long-term WHO/MDT treated multibacillary leprosy patients.
The ALERT Leprosy Control Programme introduced WHOIMDT in Ethiopia in January 1 983 . Paucibacillary patients are treated for 6 months with self-administered daily dapsone and rifampicin once monthly under supervision. Multibacillary patients are treated for a period of at least 2 years or until the skin smears become negative. Treatment consists of self-administered dapsone, clofazimine and ri...
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هدف از این مطالعه بررسی امکان استفاده از داروهای شناخته شده در درمان سایر بیماریها به عنوان داروهای ضد سرطان است. همچنین با استفاده از این داروها در ساختمان کمپلکس فلز می توان شاخص های دارویی بدست آمده را بررسی نمود. داروی ضد ویروس ایدز(hiv)به نام زیدوودین(azt)انتخاب و.کمپلکس.محلول.در.آب[pt(azt)2]cl2سنتزو به روشهای مختلف فیزیکی و شیمیایی شناسایی گردید. بر هم کنش مقایسه ای این دارو و کمپلکس پلا...
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The stable incidence of new leprosy cases suggests that transmission of infection is continuing despite the worldwide implementation of multidrug therapy programs. Highly specific tools are required to accurately diagnose asymptomatic and early stage Mycobacterium leprae infections which are the likely sources of transmission and cannot be identified by using the detection of antibodies against...
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Mycobacteria leprae isolates obtained from 37 referral relapse cases of leprosy (37 skin and 10 nerve biopsy samples) received during the years 1994-2001, were tested for viability and drug sensitivity in the mouse footpad. A significant M. leprae yield in the footpads of control mice was obtained, with 32/47 (68%) isolates (from 26 cases) thus confirming viability. Of the 28 isolates successfu...
متن کاملPyrimidine biosynthesis de novo in M. leprae.
Mycobacterium leprae can synthesise pyrimidines de novo. Although pyrimidine synthesis could not be detected in intact bacteria, extracts contained all four enzymes unique to the de novo pathway which are detectable in mycobacteria by the methods used. Inhibition of aspartate transcarbamylase by UTP and ATP suggested that lack of pyrimidine synthetic activity in whole M. leprae could be a resul...
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ژورنال
عنوان ژورنال: Repura
سال: 1976
ISSN: 0024-1008,2185-1352
DOI: 10.5025/hansen1930.45.1_1